Then there is the fact that fire and sunlight are the bane of their existance. The first thing to be noticed is the ever-present Beast, the name given to the urges that drive vampires away from their Humanity (one of them being an endless thirst for the blood of the living). The mortals killed and brought back as vampires are in for a tough existence. But one thing is for sure, vampires have stalked and preyed on humanity for a very long time. Some believe that they were cursed by The Powers That Be for a specific purpose, others believe that vampires are a concealed part of the natural world and there are those who think it's not important at all.
In Requiem nobody knows exactly how the vampirism curse started. Players take the roles of vampires, people Cursed with eternal (un)life, supernatural power, and - oh, yeah - bloodlust and a fatal sunlight allergy. A tabletop roleplaying game in the Chronicles of Darkness line and Spiritual Successor of Vampire: The Masquerade.